In this work is *given, with a dose of conditionality, a new concept for the ingredients of the results of action of one or another combination of the genetic determinants. First is the action of the so cold non-Mendelian -, cytoplasmic -, or preferred by the author of this article extrachromosomal inheritance (heredity), valid for all the bionta, exluding the species of pre-cellular organisms. That is why, the sum of the action of these genetic determinants is *named ech-zigosis and ech-osis or eci-zigosis and eci-osis, and *designated with the symbol d eci. The second sum of actions is the *named as hemizygosis or hemisis, *marked with the symbol d hem. The third sum of actions is named homosis or - **homozygosis, here *designated as d hom. And the fourth sum of actions is - the heterozygosis or heterosis, here *symbolized as d het. The last three single summary effects are *joined together, and *named with the terms ch-osis and ch-zygosis or ci-osis and ci-zygosis, and their total sum is *marked with the symbol d ci. *New terms are also implemented for the summary effect of the whole or holistic combination of the hereditary determinants - holozygosis or holosis. For the pre-cellular organisms are suitable only the terms hemisis and holosis. But the terms ech-osis or eci-osis, hemisis , ch-osis or ci-osis and holosis are suitable for all the species of prokaryotes, and during all the phases from the *so-named stadium of gametobiont, being either *androgametobiont or *gynogametobiont, from the particular contiguous windings (generations) of the screw lines of the survivals of the birth populations of eukaryotes, either diploid, auto- or allopolyploid. The terms ech-zigosis (eci-zigosis), hemizygosis, homozygosis, heterozygosis, ch-zygosis (ci-zygosis) and holozygosis are suitable during all the phases from the *so-named stadium of zygotobiont from the particular contiguous windings (generations) of the screw lines of the survivals of the birth populations of eukaryotes, either diploid, auto- or allopolyploid, while in these circumstances the terms homosis and heterosis have not to be used. This whole or holistic effect is *designated with the symbol e hol , and is composed by the sum of the four summary single effects and by the addition of all possible interactions between them. Interactions are *labeled with the symbol b with subscripts for the respective double, triple or quadruple combination of ech (eci), ch (ci), hem, hom and het. Mathematical expressions of the holozygosis - or the holosis in any definite environment are *given with the respective specific equations for the pre-cellular organisms, for the prokaryotes or during all the phases of the aforementioned stadium of gametobiont of the eukaryotes, and during all the phases of the aforementioned stadium of zygotobiont of the eukaryotes. This new concept is also a theoretical basis, allows to create: Firstly, effective, far more perfect, and at the same time much more efficient and significantly more effective new - and advanced classical technologies for melioration of the heredity of the managed amphimictic bionts. Secondly, it is a foundation for the creation of new systems with similar merits for the preservation in orthobiosis of genetic resources at least from the amphimictic bionts both in economic practice and in nature. And this is essentially a solution, at least in this aspect, to the problem of biodiversity conservation, in which amphimictic bionts are emblematic or dominant organisms.